Ajaduo 25/5 (empagliflozin 25 mg / linagliptin 5 mg)

Ajaduo 25/5 is a combination medication containing empagliflozin (25mg) and linagliptin (5mg). Empagliflozin inhibits the sodium-glucose cotransporter 2 (SGLT2) while linagliptin inhibits dipeptidyl peptidase-4 (DPP-4). This medication is prescribed as an adjunct to diet and exercise to help improve glycemic control in adults with type 2 diabetes mellitus. Furthermore, empagliflozin, one of the active ingredients in Ajaduo 25/5, is also indicated for lowering the risk of cardiovascular death in adults with type 2 diabetes mellitus and established cardiovascular disease.

However, there are certain limitations to using this product. It is not recommended for patients with type 1 diabetes mellitus due to the increased risk of diabetic ketoacidosis. Additionally, there is insufficient data on its use in patients with a history of pancreatitis. Finally, it is not advised to use this medication to improve glycemic control in adults with type 2 diabetes mellitus and an estimated glomerular filtration rate (eGFR) of less than 30 mL/min/1.73 m2.

Ajaduo Dosage:

It is important to evaluate renal function before starting and as needed. The suggested daily dosage for Ajaduo involves taking 10 mg of empagliflozin and 5 mg of linagliptin in the morning, with or without food. The dosage can be raised to a maximum of 25 mg of empagliflozin and 5 mg of linagliptin per day.

Ajaduo 25 5 tablet price 

Ajaduo 25 5 tablet price in India is only 9% of the cost of other countries. 

Ajaduo Side Effects:

• Pancreatitis: Inform your healthcare provider if you have a history of pancreatitis, gallstones, alcoholism, or high triglyceride levels. Stop taking the medication and call your doctor immediately if you experience severe abdominal pain that radiates to your back, with or without vomiting.
• Ketoacidosis: This is a serious condition that requires immediate hospital treatment. Even if your blood sugar is less than 250 mg/dL, ketoacidosis can occur in people with type 1 or type 2 diabetes who take AJADUO. Contact your healthcare provider right away or go to the nearest emergency room if you experience symptoms such as nausea, vomiting, abdominal pain, fatigue, or difficulty breathing. Check your urine for ketones if possible.
• Dehydration: This can make you feel dizzy, faint, lightheaded, or weak, especially when you stand up. If you take medication to lower your blood pressure or are on a low-salt diet, have kidney problems, or are over 65 years of age, you may be at higher risk of dehydration. Talk to your healthcare provider about how much fluid you should drink daily, especially if you are ill or unable to eat or drink normally.
• Serious urinary tract infections: Symptoms include burning sensation when you urinate, frequent urination, pain in your lower abdomen or pelvis, or blood in your urine. You may also experience fever, back pain, nausea, or vomiting.
• Low blood sugar (hypoglycemia): This can be caused by taking AJADUO with other medications that lower blood sugar levels, such as sulfonylureas or insulin. Signs of hypoglycemia include headache, drowsiness, weakness, confusion, irritability, hunger, fast heartbeat, sweating, dizziness, shaking, or feeling jittery.
• Necrotizing fasciitis: This is a rare but serious bacterial infection that affects the tissue under the skin around the genitals and anus. Seek medical attention immediately if you experience a fever, weakness, or discomfort and have pain, tenderness, swelling, or redness in this area.
• Vaginal or penile yeast infection: Symptoms include odor, discharge, itching, and swelling.
• Allergic reactions: Symptoms include swelling of the face, lips, tongue, throat, or other areas of the skin, difficulty swallowing or breathing, raised red areas on the skin (hives), skin rash, itching, flaking, or peeling. Stop taking AJADUO and call your healthcare provider or go to the emergency room if you experience any of these symptoms.
• Joint pain: In some people taking DPP-4 inhibitors, a medication in AJADUO, severe joint pain may occur. Contact your healthcare provider if you experience this.
• Bullous pemphigoid: This is a serious skin reaction that may require hospital treatment. Contact your healthcare provider right away if you develop blisters.
• Heart failure: Inform your healthcare provider if you have a history of heart failure before taking AJADUO.