Herduo ( lapatinib 250mg)

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$175.00 per 30 Tablets

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Indications & Dosage

Herduo (lapatinib 250mg) is a generic kinase inhibitor indicated for Breast Cancer medicine from Natco, which is a listed and the one of the largest generic pharmaceutical manufacturer in India.

Lapatinib Cost & Price :

Lapatinib 250mg’s price is $ 7650,Generic lapatinib price in India is only 10% of the Lapatinib cost

The following is the details of Lapatinib 250mg indication:

1. capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress human epidermal growth factor receptor 2 (HER2) and who have received prior therapy including an anthracycline, a taxane, and trastuzumab. Limitations of Use: Patients should have disease progression on trastuzumab prior to initiation of treatment with lapatinib in combination with capecitabine.

2.letrozole for the treatment of postmenopausal women with hormone receptor- positive metastatic breast cancer that overexpresses the HER2 receptor for whom hormonal therapy is indicated. lapatinib in combination with an aromatase inhibitor has not been compared to a trastuzumab-containing chemotherapy regimen for the treatment of metastatic breast cancer.

Lapatinib Dosage

The recommended dosage of lapatinib for advanced or metastatic breast cancer is 1,250 mg (5 tablets) given orally once daily on Days 1-21 continuously in combination with capecitabine 2,000 mg/m2/day (administered orally in 2 doses approximately 12 hours apart) on Days 1-14 in a repeating 21-day cycle.

The recommended dose of lapatinib for hormone receptor-positive, HER2-positive metastatic breast cancer is 1,500 mg (6 tablets) given orally once daily continuously in combination with letrozole. When lapatinib is coadministered with letrozole, the recommended dose of letrozole is 2.5 mg once daily.

1. lapatinib should be taken at least one hour before or one hour after a meal. However, capecitabine should be taken with food or within 30 minutes after food.

2. lapatinib should be taken once daily. Do not divide daily doses of lapatinib.

3.Modify dose for cardiac and other toxicities, severe hepatic impairment, diarrhea, and CYP3A4 drug interactions.

Long term side effects of Laptinib

lapatinib may cause serious side effects, including: • heart problems, including decreased pumping of blood from the heart and an abnormal heartbeat. Signs and

symptoms of an abnormal heartbeat include: o feeling like your heart is pounding or racing o feeling lightheaded o dizziness o shortness of breath o tiredness

Your healthcare provider should check your heart function before you start taking lapatinib and during treatment.

1.liver problems. Liver problems can be severe and deaths have happened. Signs and symptoms of liver problems include: o itching o yellowing of your skin or the white part of your eyes o dark urine o pain or discomfort in the right upper stomach area Your healthcare provider should do blood tests to check your liver before you start taking lapatinib and during treatment.

2.diarrhea. Diarrhea is common with lapatinib and may sometimes be severe. Severe diarrhea can cause loss of body fluid (dehydration) and some deaths have happened. Call your healthcare provider right away if you have a change in bowel pattern or if you have severe diarrhea. Follow your healthcare provider’s instructions for what to do to help prevent or treat diarrhea.

3.lung problems. Symptoms of a lung problem with lapatinib include a cough that will not go away or shortness of breath.

4.severe skin reactions. lapatinib may cause severe skin reactions. Tell your healthcare provider right away if you develop a skin rash, red skin, blistering of the lips, eyes, or mouth, peeling of the skin, fever, or any combination of these. As severe skin reactions can be life-threatening, your healthcare provider may tell you to stop taking lapatinib. Call your healthcare provider right away if you have any of the signs or symptoms of the serious side effects listed above. Common side effects of lapatinib in combination with capecitabine or letrozole include:

• diarrhea • red, painful hands and feet • nausea • rash • vomiting • inflamed mouth, digestive tract and airways • mouth sores • headache • unusual hair loss or thinning • shortness of breath • dry skin • itching • tiredness • painful arms, legs and back • loss of appetite • indigestion • nose bleeds • nail disorders such as nail bed changes, nail pain, infection and swelling of the cuticles • difficulty sleeping

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of lapatinib. For more information, ask your healthcare provider

Lapatinib PI

For more Prescribing information,please check the → “FDA Prescribing Information”.

Additional Info

Package Quantity150 Tablets
WarningsDon't take the drug without consulting a qualified doctor or physician
Suggested useFollow the doctor's advice
Delivery & Returns7-14 Days


2020-07-15 06:04:07
Thanks a lot

 Received my 2nd parcel after Covid-19. This is the best generic lapatinib 250mg. Appreciate so much for your kindly help during the hard time. God bless all your kindly help.

    2019-01-01 01:25:29
    The Tykerb generic helps

    India Tykerb generic really give me new life. I takes tykerb 5 pills daily at one time for 3 weeks and off for 1 week per doctor, satisfied. The generic lapatinib 250mg and Xeloda have stabilized my tumors. God bless all of you.

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      Herduo ( lapatinib 250mg)

      Herduo ( lapatinib 250mg)

      Lapatinib 250mg


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