Bdron ( Abiraterone 500 )

Bdron, or commonly known as Abiraterone 500, is a drug that works by inhibiting CYP17. It is prescribed in combination with prednisone for the treatment of metastatic castration-resistant prostate cancer (CRPC) or metastatic high-risk castration-sensitive prostate cancer (CSPC) patients.

Abiraterone acetate Dosage

To treat metastatic castration-resistant prostate cancer, patients should take Abiraterone 1,000mg orally once a day, along with prednisone 5mg taken orally twice daily. Patients with metastatic castration-sensitive prostate cancer should take Abiraterone 1,000mg orally once a day, along with prednisone 5mg taken orally once a day. In addition, it is crucial that patients taking Abiraterone also receive a gonadotropin-releasing hormone (GnRH) analog at the same time or have undergone bilateral orchiectomy.

Abiraterone tablets should be taken once daily as a single dose on an empty stomach. Patients should not eat food for 2 hours before and 1 hour after taking Abiraterone. The tablets should be swallowed whole with water and should not be crushed or chewed.

Dose adjustments may be necessary for some patients. For those with moderate hepatic impairment (Child-Pugh Class B) at baseline, the starting dose of Abiraterone should be reduced to 250mg once daily. If patients experience hepatotoxicity during treatment, Abiraterone should be stopped until they recover, and then retreatment may begin at a lower dose. Severe hepatotoxicity may require discontinuation of Abiraterone altogether.

Abiraterone 500 mg price

Abiraterone acetate 500mg can be purchased in India at a cost that is only 10% of what it costs in other countries.

Abiraterone side effect

Abiraterone has the potential to cause severe side effects, including hypertension, edema, and hypokalemia (low potassium levels in the blood). It is crucial to notify your healthcare provider immediately if you experience any of the following symptoms:

• Dizziness or lightheadedness
• Rapid or irregular heartbeat
• Headache
• Confusion
• Muscle weakness
• Pain or swelling in the legs
• Fainting
• Swelling in the feet or legs

Stopping prednisone, contracting an infection, or experiencing stress can lead to adrenal problems. Liver problems are also a potential risk and may cause changes in liver function blood tests. Your healthcare provider will conduct liver function blood tests before and during Abiraterone treatment. Liver failure can be fatal, so it is vital to inform your healthcare provider of any changes, such as:

• Yellowing of the eyes or skin
• Darkening of urine
• Severe vomiting or nausea

Common side effects of Abiraterone include joint pain or swelling, leg or feet swelling, weakness, cough, vomiting, hot flashes, diarrhea, high blood pressure, shortness of breath, urinary tract infection, anemia, hypokalemia, hyperglycemia, high blood cholesterol or triglycerides, and abnormal blood test results. If any side effects persist or cause concern, contact your healthcare provider.

Please note that this list is not exhaustive. For more information on Abiraterone and how to prescribe it, please refer to the "FDA Prescribing Information" or consult your healthcare provider or pharmacist.