Ibrucent 140 (Ibrutinib 140mg)

Ibrucent 140 (Ibrutinib) is a kinase inhibitor used to treat:

1. Mantle cell lymphoma (MCL) who have received at least one prior therapy. Accelerated approval was granted for this indication based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.

2. Chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL).

3. Chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) with 17p deletion

4. Waldenström’s macroglobulinemia (WM)

5. Marginal zone lymphoma (MZL) who require systemic therapy and have received at least one prior anti-CD20-based therapy. Accelerated approval was granted for this indication based on overall response rate. Continued approval for this indication may be contingent upon verification and description of clinical benefit in a confirmatory trial.

6. Chronic graft versus host disease (cGVHD) after failure of one or more lines of systemic therapy

Ibrucent 140 (Ibrutinib 140mg)  Cost & Price:

Ibrucent 140 (Ibrutinib 140mg)’s price is only 5-10% of brand one.

Ibrucent 140 (Ibrutinib 140mg) new package

Due to too many fake Ibrucent 140 (Ibrutinib 140mg) in India and China, Incepta start to use the new package which can be authentic verified from April, 2019

Ibrutinib DOSAGE

1.MCL and MZL: 560 mg taken orally once daily (four 140 mg capsules once daily)

2.CLL/SLL, WM, and cGVHD: 420 mg taken orally once daily (three 140 mg capsules once daily).

Capsules should be taken orally with a glass of water. Do not open, break, or chew the capsules

Ibrutinib 140mg side effects:

diarrhea muscle and bone pain rash • nausea • bruising • tiredness • fever

The most common side effects of IMBRUVICA in adults with cGVHD include:

tiredness bruising • diarrhea • mouth sores (stomatitis) • muscle spasms

• nausea • pneumonia

Diarrhea is a common side effect in people who take IMBRUVICA. Drink plenty of fluids during treatment with IMBRUVICA to help reduce your risk of losing too much fluid (dehydration) due to diarrhea. Tell your healthcare provider if you have diarrhea that does not go away.

Ibrutinib PI

For more Prescribing information，please check the → “FDA Prescribing Information”.