Nindev 150, also known as nintedanib 150 mg, is a generic drug that functions as a kinase inhibitor. Its typical uses include managing idiopathic pulmonary fibrosis (IPF), treating chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype, and decelerating the decline of pulmonary function in individuals with systemic sclerosis-associated interstitial lung disease (SSc-ILD).
1. The suggested dosage for this medication is 150 mg taken twice daily, with food and spaced out by approximately 12 hours. However, individuals with mild hepatic impairment (Child Pugh A) should take 100 mg twice daily, also with food and spaced approximately 12 hours apart.
2. If unfavorable reactions occur, it may be necessary to temporarily reduce the dosage to 100 mg, halt treatment temporarily, or discontinue it entirely.
3. Before starting the medication, all patients should undergo liver function tests, and females of reproductive age should undergo a pregnancy test.
Nintedanib 150 mg price in India
In India, the available brand names for Nintedanib 150 mg are Nindev 150, and it is priced at only 75 USD for a pack of 10 capsules. However, in other countries, the cost of Nintedanib is approximately 2960 USD for a pack of 10 capsules.
Nintedanib 150 mg side effects
If you encounter any unexplained symptoms such as yellowing of the skin or white part of the eyes (jaundice), upper right abdominal pain, dark or tea-colored urine, abnormal bleeding or bruising, fatigue, or loss of appetite, seek immediate medical attention as these symptoms could indicate liver problems. Your doctor will monitor your liver function through blood tests prior to and during treatment with nintedanib.
While taking nintedanib, you may experience diarrhea, nausea, or vomiting. Your doctor may recommend drinking fluids or taking medication to manage these side effects. Notify your doctor if these symptoms persist or worsen, or if you are taking laxatives, stool softeners, or other medications or supplements that cause diarrhea.
Inform your doctor right away if you feel chest pain, pressure, pain in the arms, back, neck, or jaw, or shortness of breath as these may indicate a heart attack. Similarly, if you experience numbness or weakness on one side of your body, difficulty speaking, headache, or dizziness, inform your doctor immediately as these may indicate a stroke.
Taking nintedanib may increase the risk of bleeding problems. If you experience unusual bleeding, bruising, or wounds that do not heal, or if you are taking blood thinners (including prescription medications and over-the-counter aspirin), inform your doctor.
Using nintedanib may also increase the risk of developing a tear in your stomach or intestinal wall (perforation). Notify your doctor if you experience stomach area pain or swelling.
The most common side effects of nintedanib include diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.
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